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Cefminox (sodium) (Standard)

Cefminox (sodium) (MT-141) (Standard) is the analytical standard of Cefminox (sodium) . This product is intended for research and analytical applications. Cefminox sodium is a semisynthetic cephamycin, which exhibits antibacterial activity. Cefminox sodium is a broad-spectrum, bactericidal cephalosporin antibiotic. Cefminox sodium also acts as a dual agonist of prostacyclin receptor (IP) and PPARγ. Cefminox sodium upregulates cAMP production and PTEN expression and inhibits Akt/mTOR signaling. Cefminox sodium also prevents pulmonary arterial hypertension in rat model[1][2].

Product Specifications

CAS Number

75498-96-3

Product Name Alternative

MT-141 (Standard)

UNSPSC

12352005

Target

Akt; Antibiotic; Bacterial; mTOR; PPAR; Prostaglandin Receptor; PTEN; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; GPCR/G Protein; Metabolic Enzyme/Protease; Others; PI3K/Akt/mTOR; Vitamin D Related/Nuclear Receptor

Field of Research

Infection; Cardiovascular Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/cefminox-sodium-standard.html

Smiles

O=C(C(N12)=C(CSC3=NN=NN3C)CS[C@]2([H])[C@](OC)(NC(CSC[C@@H](N)C(O)=O)=O)C1=O)O[Na]

Molecular Formula

C16H20N7NaO7S3

Molecular Weight

541.56

References & Citations

[1]Inouye S, et al. In vitro and in vivo antibacterial activities of MT-141, a new semisynthetic cephamycin, compared with those of five cephalosporins. Antimicrob Agents Chemother. 1984 Nov;26 (5) :722-9.|[2]Xia J, et al. Cefminox, a Dual Agonist of Prostacyclin Receptor and Peroxisome Proliferator-Activated Receptor-Gamma Identified by Virtual Screening, Has Therapeutic Efficacy against Hypoxia-Induced Pulmonary Hypertension in Rats. Front Pharmacol. 2018 Feb 23;9:134.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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