KRAS inhibitor-33
KRAS inhibitor-33 (compound 115a) is an inhibitor of pyridopyrimidine kras (IC50 ≤ 100nM) [1].
Product Specifications
UNSPSC
12352101
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-inhibitor-33.html
Smiles
O=C1CCCCC2=C(C3=C(C4=NC(OC[C@@]56CCCN5C[C@@H](C6)F)=NC(N7CCCC(C7)CCN1)=C4C=N3)F)C=C(C=C2Cl)O
Molecular Formula
C33H39ClF2N6O3
Molecular Weight
641.15
References & Citations
[1]James Paul LAJINESS, et al. Pyridopyrimidine kras inhibitors. WO2024040131A1. 2023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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