1,2-Distearoyl-sn-glycero-3-phosphocholine

<strong>1,2-Distearoyl-sn-glycero-3-phosphocholine</strong>_x000D_ <strong>Catalog number:</strong> B2010427_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 790.15_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> A high purity 1,2-Distearoyl-sn-glycero-3-phosphocholine used as well-defined liposomes with a wide array of applications in biochemistry and cellular biology._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> PC(18:0/18:0), 3-sn-Phosphatidylcholine, 1,2-distearoyl, 1,2-Dioctadecanoyl-sn-glycero-3-phosphocholine, PC, DSPC, L-β,γ-Distearoyl-α-lecithin, L-α-Phosphatidylcholine, distearoyl_x000D_ <strong>Grade:</strong> Biotechnology grade. All solid components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Norling K, Bernasconi V, Agmo Hernández V, Parveen N, Edwards K, Lycke NY,_x000D_ Höök F, Bally M. Gel Phase 1,2-Distearoyl-<i>sn</i>-glycero-3-phosphocholine-_x000D_ Based Liposomes Are Superior to Fluid Phase Liposomes at Augmenting Both Antigen_x000D_ Presentation on Major Histocompatibility Complex Class II and Costimulatory_x000D_ Molecule Display by Dendritic Cells <i>in Vitro</i>. ACS Infect Dis. 2019 Nov_x000D_ 8;5(11):1867-1878._x000D_ _x000D_ 2: Dabkowska AP, Barlow DJ, Clifton LA, Hughes AV, Webster JR, Green RJ, Quinn_x000D_ PJ, Lawrence MJ. Calcium-mediated binding of DNA to 1,2-distearoyl-sn-_x000D_ glycero-3-phosphocholine-containing mixed lipid monolayers. Soft Matter. 2014_x000D_ Mar 21;10(11):1685-95._x000D_ _x000D_ 3: Smith MC, Crist RM, Clogston JD, McNeil SE. Zeta potential: a case study of_x000D_ cationic, anionic, and neutral liposomes. Anal Bioanal Chem. 2017_x000D_ Sep;409(24):5779-5787._x000D_ _x000D_ 4: Ponpipom MM, Bugianesi RL. Isolation of 1,3-distearoyl-_x000D_ glycero-2-phosphocholine (beta-lecithin) from commercial 1,2-distearoyl-sn-_x000D_ glycero-3-phosphocholine. J Lipid Res. 1980 Jan;21(1):136-9._x000D_ _x000D_ 5: Tien Sing Young RV, Tabrizian M. Rapid, one-step fabrication and loading of_x000D_ nanoscale 1,2-distearoyl-sn-glycero-3-phosphocholine liposomes in a simple,_x000D_ double flow-focusing microfluidic device. Biomicrofluidics. 2015 Jul_x000D_ 1;9(4):046501._x000D_ _x000D_ 6: Briuglia ML, Rotella C, McFarlane A, Lamprou DA. Influence of cholesterol on_x000D_ liposome stability and on in vitro drug release. Drug Deliv Transl Res. 2015_x000D_ Jun;5(3):231-42._x000D_ _x000D_ 7: Santaren JF, Rico M, Guilleme J, Ribera A. Thermal and 13C-NMR study of the_x000D_ dynamic structure of 1-palmitoyl-2-oleyl-sn-glycero-3-phosphocholine and_x000D_ 1-oleyl-2-palmitoyl-sn-glycero-3-phosphocholine in aqueous dispersions. Biochim_x000D_ Biophys Acta. 1982 May 7;687(2):231-7._x000D_ _x000D_ 8: Erdoğ A, Putra Limasale YD, Keskin D, Tezcaner A, Banerjee S. In vitro_x000D_ characterization of a liposomal formulation of celecoxib containing_x000D_ 1,2-distearoyl-sn-glycero-3-phosphocholine, cholesterol, and polyethylene glycol_x000D_ and its functional effects against colorectal cancer cell lines. J Pharm Sci._x000D_ 2013 Oct;102(10):3666-77._x000D_ _x000D_ 9: Hussain MJ, Wilkinson A, Bramwell VW, Christensen D, Perrie Y. Th1 immune_x000D_ responses can be modulated by varying dimethyldioctadecylammonium and_x000D_ distearoyl-sn-glycero-3-phosphocholine content in liposomal adjuvants. J Pharm_x000D_ Pharmacol. 2014 Mar;66(3):358-66._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/29614232/">10: Kulkarni JA, Darjuan MM, Mercer JE, Chen S, van der Meel R, Thewalt JL, Tam_x000D_ YYC, Cullis PR. On the Formation and Morphology of Lipid Nanoparticles_x000D_ Containing Ionizable Cationic Lipids and siRNA. ACS Nano. 2018 May_x000D_ 22;12(5):4787-4795. </a>_x000D_ _x000D_ <strong>Products Related to 1,2-Distearoyl-sn-glycero-3-phosphocholine </strong> <a href="https://moleculardepot.com/product-category/Chemicals/">: Chemicals</a>