KSR1 Recombinant Rabbit Monoclonal Antibody [JE57-75]
Kinase suppressor of Ras 1 is an enzyme that in humans is encoded by the KSR1 gene. Enables 14-3-3 protein binding activity; ATP binding activity; and protein C-terminus binding activity. Involved in positive regulation of MAPK cascade. Located in endoplasmic reticulum and membrane. Part of protein-containing complex. Implicated in breast adenocarcinoma. Biomarker of breast cancer.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
KSR1, KSR
Swiss Prot
Q8IVT5 Human, Q61097 Mouse,
Cellular Locus
Cytoplasm, Membrane, Cell membrane, Cell projection, ruffle membrane, Endoplasmic reticulum membrane.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within Human KSR1 aa 874-923 / 923.
Isotype
IgG
Clone
JE57-75
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
293T cell lysate, HeLa cell lysate, HT-29 cell lysate, HDLM-2 cell lysate, C2C12 cell lysate, C6 cell lysate, human cervical carcinoma tissue, C6.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:200 ;FC: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 102 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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