LIN28 inhibitor LI71 enantiomer
Product Specifications
UNSPSC Description
LIN28 inhibitor LI71 enantiomer is the enantiomer of LIN28 inhibitor LI71 with less active. LIN28 inhibitor LI71 is a potent and cell-permeable LIN28 inhibitor, which abolishes LIN28-mediated oligouridylation with an IC50 of 7 uM[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lin28-inhibitor-li71-enantiomer.html
Purity
99.83
Solubility
DMSO : 2.7 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(O)C1=CC=C([C@H]2NC3=C(C=CC=C3OCC)[C@]4([H])[C@@]2([H])CC=C4)C=C1
Molecular Weight
335.40
References & Citations
[1]Wang L, et al. Small-Molecule Inhibitors Disrupt let-7 Oligouridylation and Release the Selective Blockade of let-7 Processing by LIN28. Cell Rep. 2018;23(10):3091-3101.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-123905A/LIN28-inhibitor-LI71-enantiomer-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-123905A/LIN28-inhibitor-LI71-enantiomer-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
9007-83-4
Available Sizes
Curated Selection
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