Folic acid (disodium)

Folic acid disodium (Vitamin B9 disodium; Vitamin M disodium) is an orally active disodium salt form of Folic acid (HY-16637) with an intrinsic dissolution rate (IDR) of 4.96·105 g/s[1]. Folic acid disodium serves as cofactor in single-carbon transfer reactions and exhibits protective effects against neural tube defects, ischemic events, and cancer. Folate acid disodium overload leads to impaired brain development in embryogenesis and promotes growth of precancerous altered cells. Folic acid deficiency leads to megaloblastic anemia[2].

Product Specifications

CAS Number

[29704-76-5]

Product Name Alternative

Vitamin B9 (disodium) ; Vitamin M (disodium)

UNSPSC

12352005

Target

DNA/RNA Synthesis; Endogenous Metabolite

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer; Neurological Disease; Others

Assay Protocol

https://www.medchemexpress.com/folic-acid-disodium.html

Purity

98.56

Solubility

H2O : ≥ 100 mg/mL

Smiles

O=C(O[Na])CC[C@@H](C(O[Na])=O)NC(C1=CC=C(NCC2=CN=C3N=C(N)NC(C3=N2)=O)C=C1)=O

Molecular Formula

C19H17N7Na2O6

Molecular Weight

485.36

References & Citations

[1]Braga D., et al., Folic Acid in the Solid State: A Synergistic Computational, Spectroscopic, and Structural Approach, Crystal Growth & Design, 2016, 16, 4, 2218–222.|[2]Shulpekova Y, et al., The Concept of Folic Acid in Health and Disease. Molecules. 2021 Jun 18;26 (12) :3731.