(E/Z) -DMU2139
(E/Z) -DMU2139 (Compound 180) is the E/Z isomer of DMU2139 (HY-101285) . (E/Z) -DMU2139 is a potent and specific CYP1B1 inhibitor (IC50: 4 nM) [1].
Product Specifications
CAS Number
[104890-70-2]
UNSPSC
12352005
Target
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e-z-dmu2139.html
Smiles
O=C(C1=CC=C2C=C(OC)C=CC2=C1)/C=C/C3=CC=CN=C3
Molecular Formula
C19H15NO2
Molecular Weight
289.33
References & Citations
[1]Wang Y, et al. Carvedilol serves as a novel CYP1B1 inhibitor, a systematic drug repurposing approach through structure-based virtual screening and experimental verification. Eur J Med Chem. 2020 May 1;193:112235.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
EH0701 96 Tests
Human LRP2 (Low-density lipoprotein receptor-related protein 2) ELISA Kit
Sign In for Pricing
View Details LS084129-100ug 100 µg
ACAD11 (NM_032169) Human Over-expression Lysate
Sign In for Pricing
View Details 
abx258396-01 96 Tests
Human High Sensitive Apolipoprotein L (APOL1) ELISA Kit
Sign In for Pricing
View Details abx258396-02 5x 96 Tests
Human High Sensitive Apolipoprotein L (APOL1) ELISA Kit
Sign In for Pricing
View Details abx258396-03 10x 96 Tests
Human High Sensitive Apolipoprotein L (APOL1) ELISA Kit
Sign In for Pricing
View Details LS004101-20ug 20 µg
MAGEA2 (NM_005361) Human Over-expression Lysate
Sign In for Pricing
View Details