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(E/Z) -DMU2139

(E/Z) -DMU2139 (Compound 180) is the E/Z isomer of DMU2139. (E/Z) -DMU2139 is a potent and specific CYP1B1 inhibitor (IC50: 4 nM).

Product Specifications

CAS Number

104890-70-2

UNSPSC

12352005

Target

Cytochrome P450

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/e-z-dmu2139.html

Smiles

O=C(C1=CC=C2C=C(OC)C=CC2=C1)/C=C/C3=CC=CN=C3

Molecular Formula

C19H15NO2

Molecular Weight

289.33

References & Citations

[1]Wang Y, et al. Carvedilol serves as a novel CYP1B1 inhibitor, a systematic drug repurposing approach through structure-based virtual screening and experimental verification. Eur J Med Chem. 2020 May 1;193:112235.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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