CD15 / FUT4 / Lewis x (FR4A5), 0.2mg/mL
CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on more than 95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin'€TMs disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors. This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.
Product Specifications
Synonyms
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
FUT4
Gene ID
2526
NCBI Gene ID
654379
UniProt
P22083
Swiss Prot
P22083
Host
Mouse
Species Reactivity
Human
Reactivity
CD15|FUT4|Lewis-x
Immunogen
Myelomonocytic leukemia cells
Target Antigen
CD15 | FUT4 | Lewis-x
Clonality
Monoclonal
Clone
FR4A5
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow (verified) |IF (verified)
Field of Research
Immunology
Positive Control
U937 cells, Reed-Sternberg's cells in Hodgkin's lymphoma
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
~220 kDa (Glycoprotein)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Product Datasheet
https://cdn.gentaur.com/products/37/867308/datasheet/bnub0504-100.pdf
Product MSDS
https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf
Fragment
IgM, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
CAS Number
9007-83-4
Conjugate
Purified, with BSA
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