CD147 (CB43), 1mg/mL
CD147 is a transmembrane glycoprotein of the immunoglobulin superfamily. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is involved in the regulation of matrix remodeling at the epidermal-dermal interface. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis.This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.
Product Specifications
CAS Number
9007-83-4
Synonyms
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
BSG
Gene ID
682
NCBI Gene ID
501293
UniProt
P35613
Swiss Prot
P35613
Host
Mouse
Species Reactivity
Human
Reactivity
CD147
Immunogen
Native human leucocytes
Target Antigen
CD147
Clonality
Monoclonal
Clone
CB43
Type
Primary
Source
Animal
Origin
Animal
Field of Research
Cancer, Developmental biology
Positive Control
HSB2 cells. Renal Cell, Ovarian carcinoma or Melanoma
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
35 kDa (non-reduced) ; 40 kDa (reduced)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgM
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free
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