IONIS-GCCRRx
IONIS-GCCRRx (ISIS 426115), a glucocorticoid receptor antagonist, is a 2'-O-methoxyethyl (2'-MOE) antisense oligonucleotide (ASO) [1].
Product Specifications
CAS Number
1431900-72-9
Product Name Alternative
ISIS 426115
UNSPSC
12352208
Target
Glucocorticoid Receptor
Type
Oligonucleotides
Related Pathways
Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ionis-gccrrx.html
Purity
90.52
Smiles
[IONIS-GCCRRx]
References & Citations
[1]Lijiang Shen, et al. Mechanistic understanding for the greater sensitivity of monkeys to antisense oligonucleotide-mediated complement activation compared with humans. J Pharmacol Exp Ther. 2014 Dec;351 (3) :709-17. |[2]Gaurav Chikara, et al. A Narrative Review of Potential Future Antidiabetic Drugs: Should We Expect More? Indian J Clin Biochem. 2018 Apr;33 (2) :121-131.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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