TRP-601
TRP-601 is a caspase inhibitor. TRP-601 reversed the increased expression of active caspase-2, the activation of endogenous apoptotic pathway and the up-regulation of key protein triggered by hyperoxia[1].
Product Specifications
CAS Number
[1094569-02-4]
UNSPSC
12352209
Target
Bcl-2 Family; Caspase
Type
Peptides
Related Pathways
Apoptosis
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/trp-601.html
Solubility
10 mM in DMSO
Smiles
FC(C=CC=C1F)=C1OCC(C(CC(OC)=O)NC([C@H](C)NC([C@H](C(C)C)NC([C@H](CC(OC)=O)NC([C@H](C(C)C)NC(C2=NC3=C(C=CC=C3)C=C2)=O)=O)=O)=O)=O)=O
Molecular Formula
C40H48F2N6O11
Molecular Weight
826.84
References & Citations
[1]M Sifringer, et al. Prevention of neonatal oxygen-induced brain damage by reduction of intrinsic apoptosis. Cell Death Dis. 2012 Jan 12;3 (1) :e250. |[2]Sifringer M, et al. Prevention of neonatal oxygen-induced brain damage by reduction of intrinsic apoptosis [J]. Cell death & disease, 2012, 3 (1) : e250-e250.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
Bcl-2; Caspase 2; Caspase 3
Curated Selection
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