Taxamairin B
Taxamairin B is a potent anti-inflammatory agent. Taxamairin B decreases proinflammatory cytokines (TNF-α, IL-1β and IL-6) expression and the production of NO and ROS in LPS-induced RAW264.7 cells. Taxamairin B exhibits significant protective effects in LPS-induced acute lung injury in mice[1][2].
Product Specifications
CAS Number
110300-77-1
UNSPSC
12352005
Target
Interleukin Related; PI3K; Reactive Oxygen Species (ROS) ; TNF Receptor
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/taxamairin-b.html
Solubility
10 mM in DMSO
Smiles
CC(C1=C2)(C)C(C=CC1=CC3=C(C=C(C(C)C)C(OC)=C3OC)C2=O)=O
Molecular Formula
C22H24O4
Molecular Weight
352.42
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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