Retelliptine
Retelliptine (BD84), a derivative of ellipticine, is an inhibitor of Topoisomerase II with anticancer activity. Retelliptine can bind to DNA and inhibit Topoisomerase II during DNA replication[1][2].
Product Specifications
CAS Number
72238-02-9
Product Name Alternative
BD84
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/retelliptine.html
Smiles
CCN(CC)CCCNC1=NC=CC2=C(C)C3=C(C4=CC(OC)=CC=C4N3)C(C)=C21
Molecular Formula
C25H32N4O
Molecular Weight
404.55
Precautions
P264-P270-P280-P302+P352-P330-P362+P364-P501
References & Citations
[1]Kattan J, et al. Phase I study of retelliptine dihydrochloride (SR 95325 B) using a single two-hour intravenous infusion schedule[J]. American journal of clinical oncology, 1994, 17 (3) : 242-245.|[2]Maulard C, et al. Binding of retelliptine, a new antitumoral agent, to serum proteins and erythrocytes[J]. Biochemical pharmacology, 1990, 40 (4) : 895-898.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Frequently Asked Questions
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