Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Bromhexine (hydrochloride) (Standard)

Bromhexine (hydrochloride) (Standard) is the analytical standard of Bromhexine (hydrochloride) . This product is intended for research and analytical applications. Bromhexine hydrochloride is a potent and specific TMPRSS2 protease inhibitor with an IC50 of 0.75 μM. Bromhexine hydrochloride can prevent and manage SARS-CoV-2 infection. Bromhexine hydrochloride is an autophagy agonist. Bromhexine hydrochloride is a mucolytic cough suppressant and has the potential for a range of respiratory conditions[1][2][3][4].

Product Specifications

CAS Number

611-75-6

UNSPSC

12352005

Target

Autophagy; HIV; Reference Standards; SARS-CoV

Type

Reference Standards

Related Pathways

Anti-infection; Autophagy; Others

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/bromhexine-hydrochloride-standard.html

Smiles

CN(C1CCCCC1)CC2=CC(Br)=CC(Br)=C2N.Cl

Molecular Formula

C14H21Br2ClN2

Molecular Weight

412.59

References & Citations

[1]Jared M Lucas, et al. The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis. Cancer Discov. 2014 Nov;4 (11) :1310-25.|[2]Li Wen Shen, et al. TMPRSS2: A potential target for treatment of influenza virus and coronavirus infections. Biochimie. 2017 Nov;142:1-10.|[3]Roberto Maggio, et al. Repurposing the mucolytic cough suppressant and TMPRSS2 protease inhibitor bromhexine for the prevention and management of SARS-CoV-2 infection. Pharmacol Res. 2020 Jul;157:104837.|[4]Santosh Chauhan, et al. Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential. Nat Commun. 2015 Oct 27;6:8620.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

SIRT6-IN-1
TRC-S487908-100MG 100 mg

SIRT6-IN-1

Sign In for Pricing
View Details
D-Allose
TRC-A548005-1G 1 g

D-Allose

Sign In for Pricing
View Details
Sel1l3 Mouse Gene Knockout Kit (CRISPR)
KN515482 1 Kit

Sel1l3 Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
eIF5A Recombinant Rabbit Monoclonal Antibody [SC60-09]
ET1610-49 100 µL

eIF5A Recombinant Rabbit Monoclonal Antibody [SC60-09]

Sign In for Pricing
View Details
Ketohexokinase Recombinant Rabbit monoclonal Antibody
HA750860 100 µL

Ketohexokinase Recombinant Rabbit monoclonal Antibody

Sign In for Pricing
View Details
4-Phenyl-1,2,4-triazoline-3,5-dione
TRC-P337380-5G 5 g

4-Phenyl-1,2,4-triazoline-3,5-dione

Sign In for Pricing
View Details