CD11a (Cris-3), CF568 conjugate, 0.1mg/mL
Recognizes a protein of 180 kDa, identified as CD11a (Leucocyte Workshop II; Code N202) . CD11a complex with the 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a /C18 (aLbL) . LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
CAS Number
9007-83-4
Synonyms
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ITGAL
Gene ID
3683
NCBI Gene ID
174103
UniProt
P20701
Swiss Prot
P20701
Host
Mouse
Species Reactivity
Human
Reactivity
CD11a
Immunogen
Stimulated human leukocytes
Target Antigen
CD11a
Clonality
Monoclonal
Clone
Cris-3
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow (verified) |Functional studies (published)
Field of Research
Immunology
Positive Control
JY, HUT-78, MOLT-4, HL60, U937, and human leukocytes. Human lymph nodes and tonsils.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
180 kDa
References & Citations
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Product Datasheet
https://cdn.gentaur.com/products/37/866679/datasheet/bnc680151-500.pdf
Product MSDS
https://cdn.gentaur.com/products/37/68dd02ad061270361e10855f/msds/bnc680151-500.pdf
Fragment
IgG2b, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF568
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