CD104 (UM-A9), CF647 conjugate, 0.1mg/mL

CD104 is beta 4 integrin. It is primarily expressed in epithelial cells. Together with alpha 6 integrin, it is the cell surface receptor for laminin, where it mediates cell adhesion. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

CAS Number

9007-83-4

Synonyms

CD104; Integrin beta 4; ITGB4; GP150

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

ITGB4

Gene ID

3691

NCBI Gene ID

632226

UniProt

P16144

Swiss Prot

P16144

Host

Mouse

Species Reactivity

Human

Reactivity

CD104|integrin beta 4

Immunogen

Human squamous cell carcinoma (UM-SCC1)

Target Antigen

CD104 | integrin beta 4

Clonality

Monoclonal

Clone

UM-A9

Type

Primary

Source

Animal

Origin

Animal

Applications

Flow, surface (published) |Functional studies (published) |IF (published) |IP (published)

Field of Research

Cancer, Immunology

Positive Control

A431 cells, squamous cell carcinoma, colon or placenta

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

205 kDa

References & Citations

Note: References for this clone sold by other suppliers may be listed for expected applications. Cancer Res (1991) 51(9):2395-402. (IP, functional studies) Cancer Res (1997) 57(1), 38-42. (IP, Flow, IF)