CD100 (133-1C6), 0.2mg/mL

CD100 (also known as Semaphorin 4D), is a homodimeric protein comprised of 50 kDa subunits. It is expressed on resting T cells and weakly on other lymphocytes, and its expression is increased on B and T cells after stimulation. CD100 is a cell surface receptor that binds to CD72, Plexin B1 and Plexin B2. It promotes B cell aggregation, cell survival, and cell proliferation.

Product Specifications

CAS Number

9007-83-4

Synonyms

CD100; Semaphorin-4D; SEMA4D

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

SEMA4D

Gene ID

10507

NCBI Gene ID

494406

UniProt

Q92854

Swiss Prot

Q92854

Host

Mouse

Species Reactivity

Baboon,Human

Reactivity

CD100|Semaphorin-4D

Immunogen

PHA stimulated human peripheral blood lymphocytes.

Target Antigen

CD100 | Semaphorin-4D

Clonality

Monoclonal

Clone

133-1C6

Type

Primary

Source

Animal

Origin

Animal

Applications

Flow, surface (published) |Functional studies (published) |ELISA (published)

Field of Research

Immunology, Neuroscience, Signal transduction

Positive Control

Daudi, Raji, HUT-78, Kg1a, U937, and human lymphocytes. Human tonsils and lymph nodes.

Stability

2 years

Concentration

0.2 mg/mL

Buffer

PBS, 0.05% BSA, 0.05% azide

Molecular Weight

50 kDa (Monomer)

References & Citations

Note: References for this clone sold by other suppliers may be listed for expected applications. Frontiers Immunol (2017) 8: 765. (functional studies) Frontiers Immunol (2021) 12:240. (ELISA) Paterson J., Ailles L.E. (2018) High Throughput Flow for Cell Surface Profiling. In: Hawley T., Hawley R. (eds) Flow Protocols. Methods in Molecular Biology, vol 1678. Humana Press, New York, NY. (Flow)