DPC-AJ1951

DPC-AJ1951, a 14 amino acid peptide that acts as a potent agonist of the parathyroid hormone (PTH) /PTH-related peptide receptor (PPR) . And characterized the activity of DPC-AJ1951 in ex vivo and in vivo assays of bone resorption[1].

Product Specifications

CAS Number

943519-33-3

UNSPSC

12352209

Target

Thyroid Hormone Receptor

Type

Peptides

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/dpc-aj1951.html

Solubility

H2O

Smiles

OC(C=C1)=CC=C1C[C@@H](C(N)=O)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@@H](NC([C@H](CCCC)NC([C@H](CC(C)C)NC([C@H](CCC(N)=O)NC([C@H]([C@@H](C)CC)NC([C@H](CCC(O)=O)NC(C(C)(C)NC([C@H](C(C)C)NC(C(C)(N)C)=O)=O)=O)=O)=O)=O)=O)=O)CC2=CN=CN2)=O)=O)=O)=O)=O

Molecular Formula

C76H127N23O19

Molecular Weight

1666.96

References & Citations

[1]Percy H Carter, et al. Discovery of a Small Molecule Antagonist of the Parathyroid Hormone Receptor by Using an N-terminal Parathyroid Hormone Peptide Probe. Proc Natl Acad Sci U S A. 2007 Apr 17;104 (16) :6846-51.