OS-3-106

OS-3-106 is a potent, BBB-penetrated and selective dopamine D3 receptor (D3R) agonist. OS-3-106 binds with high affinity (Ki = 0.2 nM) at the D3R. OS-3-106 can be used for psychoactivator addiction research[1].

Product Specifications

CAS Number

[1580000-17-4]

Product Name Alternative

APC

UNSPSC

12352005

Target

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/os-3-106.html

Purity

97.03

Solubility

DMSO : 83.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(NCCCCN1CCN(C2=CC=CC=C2OC)CC1)C3=CC=C(C4=CSC=N4)C=C3

Molecular Formula

C25H30N4O2S

Molecular Weight

450.60

References & Citations

[1]Cheung TH, et al. Reduction of cocaine self-administration and D3 receptor-mediated behavior by two novel dopamine D3 receptor-selective partial agonists, OS-3-106 and WW-III-55. J Pharmacol Exp Ther. 2013 Nov;347 (2) :410-23.