(±) -Indoxacarb

Indoxacarb ((±) -Indoxacarb; DPX-JW062) is a broad-spectrum oxadiazine insecticide with high insecticidal activity and low mammalian toxicity. Indoxacarb blocks insect sodium channels in nerve preparations and isolated neurons[1].

Product Specifications

CAS Number

[144171-61-9]

Product Name Alternative

(RS) -Indoxacarb; DPX-JW062

UNSPSC

12352005

Hazard Statement

H301, H317, H332, H372, H410

Target

Sodium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/racemic-indoxacarb.html

Purity

98.36

Solubility

DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1(CC2=C3C=CC(Cl)=C2)C3=NN(C(N(C(OC)=O)C4=CC=C(OC(F)(F)F)C=C4)=O)CO1)OC

Molecular Formula

C22H17ClF3N3O7

Molecular Weight

527.83

Precautions

H301, H317, H332, H372, H410

References & Citations

[1]Weizhong Song, et al. Molecular basis of differential sensitivity of insect sodium channels to DCJW, a bioactive metabolite of the oxadiazine insecticide indoxacarb. Neurotoxicology. 2006 Mar;27 (2) :237-44.