Blood Group H Type 2 (CD173) (19-OLE), 0.2mg/mL
This antibody is applicable for staining ABO blood group O. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. This antibody recognizes the blood group H type 2 antigens, trisaccharide Fuc-a-1-2Gal1-4GlcNAc-a-1. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. It is expressed on endothelial cells, epithelial cells and granulocytes. Increased expression of this antigen has been observed on some tumor tissues such as gastric carcinomas, urothelial carcinomas, and colon carcinomas.This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.
Product Specifications
CAS Number
9007-83-4
Synonyms
ABO Type O; Blood Group O; Blood Group H
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ABO
Gene ID
28
NCBI Gene ID
654423
UniProt
P16442
Swiss Prot
P16442
Host
Mouse
Species Reactivity
Human
Reactivity
Blood Group H Type-2
Immunogen
Mucinous colonic adenocarcinoma
Target Antigen
Blood Group H Type-2
Clonality
Monoclonal
Clone
19-OLE
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Hematology
Positive Control
KG1 cells or human colorectal carcinoma.
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
Multiple
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgM, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA
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