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Blood Group H Type 2 (CD173) (19-OLE), 0.2mg/mL

This antibody is applicable for staining ABO blood group O. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. This antibody recognizes the blood group H type 2 antigens, trisaccharide Fuc-a-1-2Gal1-4GlcNAc-a-1. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. It is expressed on endothelial cells, epithelial cells and granulocytes. Increased expression of this antigen has been observed on some tumor tissues such as gastric carcinomas, urothelial carcinomas, and colon carcinomas.This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.

Product Specifications

CAS Number

9007-83-4

Synonyms

ABO Type O; Blood Group O; Blood Group H

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

ABO

Gene ID

28

NCBI Gene ID

654423

UniProt

P16442

Swiss Prot

P16442

Host

Mouse

Species Reactivity

Human

Reactivity

Blood Group H Type-2

Immunogen

Mucinous colonic adenocarcinoma

Target Antigen

Blood Group H Type-2

Clonality

Monoclonal

Clone

19-OLE

Type

Primary

Source

Animal

Origin

Animal

Applications

IHC, FFPE (verified)

Field of Research

Cancer, Hematology

Positive Control

KG1 cells or human colorectal carcinoma.

Stability

2 years

Concentration

0.2 mg/mL

Buffer

PBS, 0.05% BSA, 0.05% azide

Molecular Weight

Multiple

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgM, kappa

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)

Conjugate

Purified, with BSA

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