LRRK2-IN-15
Product Specifications
UNSPSC Description
LRRK2-IN-15 is an LRRK2 inhibitor. The IC50 value for PBMC cells is 5 nM, and the IC50 value for BCRP is 1.5 μM. LRRK2-IN-15 can be used for research on Parkinson's disease[1].
Target Antigen
BCRP; LRRK2
Type
Reference compound
Related Pathways
Autophagy;Membrane Transporter/Ion Channel
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lrrk2-in-15.html
Smiles
O[C@H]1COC[C@]1(N2CCN(C3=CC4=C(C=C3Cl)C=NN4C5=CN(C6(C7)CC7C6)N=C5)CC2)C
Molecular Weight
468.98
References & Citations
[1]Logan KM, et al. Discovery and Optimization of N-Heteroaryl Indazole LRRK2 Inhibitors. J Med Chem. 2024 Sep 4.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-168041/LRRK2-IN-15-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-168041/
Clinical Information
No Development Reported
Curated Selection
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