LRRK2-IN-15
LRRK2-IN-15 is an LRRK2 inhibitor. The IC50 value for PBMC cells is 5 nM, and the IC50 value for BCRP is 1.5 μM. LRRK2-IN-15 can be used for research on Parkinson's disease[1].
Product Specifications
UNSPSC
12352005
Target
BCRP; LRRK2
Type
Reference compound
Related Pathways
Autophagy; Membrane Transporter/Ion Channel
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lrrk2-in-15.html
Smiles
O[C@H]1COC[C@]1(N2CCN(C3=CC4=C(C=C3Cl)C=NN4C5=CN(C6(C7)CC7C6)N=C5)CC2)C
Molecular Formula
C24H29ClN6O2
Molecular Weight
468.98
References & Citations
[1]Logan KM, et al. Discovery and Optimization of N-Heteroaryl Indazole LRRK2 Inhibitors. J Med Chem. 2024 Sep 4.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1360293-01 0.02 mg (E-Coli)
Recombinant Oryza sativa subsp. japonica Germin-like protein 1-2 (Os01g0705100, LOC_Os01g50900)
Ask
View Details MBS1360293-02 0.1 mg (E-Coli)
Recombinant Oryza sativa subsp. japonica Germin-like protein 1-2 (Os01g0705100, LOC_Os01g50900)
Ask
View Details MBS1360293-03 0.02 mg (Yeast)
Recombinant Oryza sativa subsp. japonica Germin-like protein 1-2 (Os01g0705100, LOC_Os01g50900)
Ask
View Details MBS1360293-04 0.1 mg (Yeast)
Recombinant Oryza sativa subsp. japonica Germin-like protein 1-2 (Os01g0705100, LOC_Os01g50900)
Ask
View Details