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Anti-Hu TROP2 PE

TROP2 is a cell surface receptor that transduces calcium signals. It belongs to carcinoma-associated antigens. Mutations of TROP2 have been associated with gelatinous drop-like corneal dystrophy.

Product Specifications

Certification

RUO

Negative Species

Mouse

Immunogen

TROP2-transfected CHO cells

Target Antigen

TROP2

Clone

TrMab-6

Applications

FC (QC tested)

Format

PE

Buffer

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

References & Citations

*Sayama Y, Kaneko MK, Kato Y: Development and characterization of TrMab‑6, a novel anti‑TROP2 monoclonal antibody for antigen detection in breast cancer. Mol Med Rep. 2021 Feb;23 (2) :92., URL: https://pubmed.ncbi.nlm.nih.gov/33300065/

Storage Conditions

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Specificity

The mouse monoclonal antibody TrMab-6 recognizes an extracellular epitope of TROP2, a type I transmembrane glycoprotein. This antibody is usefull for detection of TROP2 in breast cancer.

Applications Notes

6

Species

Pig, Human

CAS Number

9007-83-4

Isotype

Mouse IgG2b kappa

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