HIF-1α-IN-7
HIF-1α-IN-7 (Compound D13) is a potent HIF-1α inhibitor. HIF-1α-IN-7 has neuroprotective activity. HIF-1α-IN-7 can be used in Alzheimer's disease research[1].
Product Specifications
CAS Number
[3026685-76-4]
UNSPSC
12352005
Target
HIF/HIF Prolyl-Hydroxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hif-1α-in-7.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(OC)C=C1)/C=C/C2=CC(C=CC(C)(C)O3)=C3C(C4=CC=CN=C4)=C2
Molecular Formula
C26H24N2O3
Molecular Weight
412.48
References & Citations
[1]Cao R, et al. Synthesis and biological evaluations of 8-biaryl-2,2-dimethylbenzopyranamide derivatives against Alzheimer's disease and ischemic stroke. Bioorg Chem. 2024 Feb;143:107064.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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