HIF-1α-IN-7

HIF-1α-IN-7 (Compound D13) is a potent HIF-1α inhibitor. HIF-1α-IN-7 has neuroprotective activity. HIF-1α-IN-7 can be used in Alzheimer's disease research[1].

Product Specifications

CAS Number

[3026685-76-4]

UNSPSC

12352005

Target

HIF/HIF Prolyl-Hydroxylase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/hif-1α-in-7.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=CC=C(OC)C=C1)/C=C/C2=CC(C=CC(C)(C)O3)=C3C(C4=CC=CN=C4)=C2

Molecular Formula

C26H24N2O3

Molecular Weight

412.48

References & Citations

[1]Cao R, et al. Synthesis and biological evaluations of 8-biaryl-2,2-dimethylbenzopyranamide derivatives against Alzheimer's disease and ischemic stroke. Bioorg Chem. 2024 Feb;143:107064.