Benastatin C
Product Specifications
UNSPSC Description
Benastatin C is a polyketide synthase-derived benastatin that has been found in Streptomyces and has diverse biological activities. It inhibits glutathione S-transferase (GST; IC50=24 μg/mL for the rat liver enzyme).2 Benastatin C also inhibits the esterase activity of isolated porcine pancreatic lipase (IC50=10 μg/mL). It increases LPS- or concanavalin A-induced blastogenesis of isolated mouse spleen lymphocytes in a concentration-dependent manner.
Target Antigen
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/benastatin-c.html
Smiles
O=C1C(C(O)=C2C=CC3=CC(CCCCC)=CC(O)=C3C2=C4)=C4C(C)(C)C5=C1C(O)=CC(O)=C5
Molecular Weight
456.53
References & Citations
[1]Xu, et al. Molecular analysis of the benastatin biosynthetic pathway and genetic engineering of altered fatty acid-polyketide hybrids. J. Am. Chem. Soc. 129(18), 6022-6030 (2007).
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-133217/Benastatin-C-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-133217/
Clinical Information
No Development Reported
CAS Number
150151-88-5
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