Benastatin C

Product Specifications

CAS Number

[150151-88-5]

UNSPSC Description

Benastatin C is a polyketide synthase-derived benastatin that has been found in Streptomyces and has diverse biological activities. It inhibits glutathione S-transferase (GST; IC50=24 μg/mL for the rat liver enzyme).2 Benastatin C also inhibits the esterase activity of isolated porcine pancreatic lipase (IC50=10 μg/mL). It increases LPS- or concanavalin A-induced blastogenesis of isolated mouse spleen lymphocytes in a concentration-dependent manner.

Target Antigen

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/benastatin-c.html

Smiles

O=C1C(C(O)=C2C=CC3=CC(CCCCC)=CC(O)=C3C2=C4)=C4C(C)(C)C5=C1C(O)=CC(O)=C5

Molecular Weight

456.53

References & Citations

[1]Xu, et al. Molecular analysis of the benastatin biosynthetic pathway and genetic engineering of altered fatty acid-polyketide hybrids. J. Am. Chem. Soc. 129(18), 6022-6030 (2007).