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Anticancer agent 207

Product Specifications

UNSPSC Description

Anticancer agent 207 (compound 10b) is a potent anticancer agent. Anticancer agent 207 bounds to the NRAS rG4 with a KD value of 2.31 µM. Anticancer agent 207 shows cytotoxicity and decreases the expression of NRAS protein. Anticancer agent 207 shows antitumor activity[1].

Target Antigen

Ras

Type

Reference compound

Related Pathways

GPCR/G Protein;MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/anticancer-agent-207.html

Solubility

10 mM in DMSO

Smiles

CCCCN(CCCOC1=CC=C2N=C3C4=C(OC3=C(C2=C1)NCCCN)C=CC(F)=C4)CCCC

Molecular Weight

494.64

References & Citations

[1]Jia-Wei Sun, et al. Design, synthesis, and evaluation of novel quindoline derivatives with fork-shaped side chains as RNA G-quadruplex stabilizers for repressing oncogene NRAS translation. European Journal of Medicinal Chemistry. 2024, 271(5): 116406.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-163515/Anticancer-agent-207-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-163515/

Clinical Information

No Development Reported

CAS Number

9007-83-4

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