9- (2-Deoxy-beta-D-ribofuranosyl) -6-methylpurine
(2R,3S,5R) -2- (hydroxymethyl) -5- (6-methyl-9H-purin-9-yl) tetrahydrofuran-3-ol (9- (2-Deoxy-beta-D-ribofuranosyl) -6-methylpurine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[16006-64-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/9-2-deoxy-beta-d-ribofuranosyl-6-methylpurine.html
Purity
95.0
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O[C@H]1C[C@H](N2C=CC3=C2N=CN=C3C)O[C@@H]1CO
Molecular Formula
C12H15N3O3
Molecular Weight
249.27
Precautions
H302, H315, H319, H335
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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