Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2
Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
Product Specifications
CAS Number
[148579-93-5]
UNSPSC
12352203
Hazard Statement
H302-H315-H319-H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/me-triacetyl-β-d-glucopyranuronate-ph-ald-no2.html
Purity
98.58
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C(OC)[C@@H](O1)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC2=CC=C(C=O)C=C2[N+]([O-])=O
Molecular Formula
C20H21NO13
Molecular Weight
483.38
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Benatuil, Lorenzo, et al. Anti-B7-H3 antibodies and antibody drug conjugates. WO2017214339.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; Glycosidase Cleavable Linker
Available Sizes
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