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δ-Dendrotoxin

δ-Dendrotoxin is a K+ channel blocker that can be obtained from the venom of the black mamba snake. δ-Dendrotoxin can be used in the study of neurological diseases[1].

Product Specifications

CAS Number

189201-23-8

UNSPSC

12352209

Target

Potassium Channel

Type

Peptides

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/δ-dendrotoxin.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CSSC[C@@H](C(N[C@@H](C(C)C)C(NCC(O)=O)=O)=O)NC2=O)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N3[C@@H](CCC3)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC4=CC=C(C=C4)O)C(NCC(N5[C@@H](CCC5)C(N[C@@H](CSSC[C@@H](C(NCC(NCC(N[C@@H](CC(N)=O)C(N[C@@H](C)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC6=CC=CC=C6)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(O)=O)C(N[C@H]7CCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC8=O)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H]([C@@H](C)CC)C(N9[C@@H](CCC9)C(N[C@@H](CO)C(N[C@@H](CC%10=CC=CC=C%10)C(N[C@@H](CC%11=CC=C(C=C%11)O)C(N[C@@H](CC%12=CC=C(C=C%12)O)C(N[C@@H](CCCCN)C(N[C@@H](CC%13=CNC%14=CC=CC=C%13%14)C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@H]2[C@H](O)C)=O)=O)=O)NC7=O)C(N[C@@H](CC(C)C)C(N%15[C@@H](CCC%15)C(N[C@@H](CC%16=CC=CC=C%16)C(N[C@@H](CC(O)=O)C(N[C@@H](CC%17=CC=C(C=C%17)O)C(N[C@@H](CO)C(NC8)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N

Molecular Formula

C296H452N82O76S6

Molecular Weight

6567.65

References & Citations

[1]Jin L, et al. Molecular mechanism of δ-dendrotoxin-potassium channel recognition explored by docking and molecular dynamic simulations. J Mol Recognit. 2011 Jan-Feb;24 (1) :101-7.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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