Dihydroaltenuene B

Dihydroaltenuene B is a potent mushroom tyrosinase inhibitor with an IC50 of 38.33 µM. Dihydroaltenuene B shows the hydrogen bonding interactions between the 3-OH and 4’-OH and the His244, Met280 and Gly281 residues of tyrosinase[1].

Product Specifications

CAS Number

[887751-89-5]

UNSPSC

12352005

Target

Fungal; Tyrosinase

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/dihydroaltenuene-b.html

Solubility

10 mM in DMSO

Smiles

C[C@@]12[C@](C[C@H]([C@@H](C2)O)O)([H])C3=CC(OC)=CC(O)=C3C(O1)=O

Molecular Formula

C15H18O6

Molecular Weight

294.30

References & Citations

[1]Zhai YJ, et al. Structures and absolute configurations of butenolide derivatives from the isopod-associated fungus Pidoplitchkoviella terricola. Phytochemistry. 2022; 193:112981.