MUC5AC (Mucin 5AC / Gastric Mucin) (1-13M1), 1mg/mL

This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.

Product Specifications

CAS Number

9007-83-4

Synonyms

Apomucin Major Airway Glycoprotein, Mucin 5 subtype AC tracheobronchial, Mucin 5 Subtypes A And C, Mucin 5AC oligomeric mucus/gel forming, Tracheobronchial Mucin (TBM)

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

MUC5AC

Gene ID

4586

NCBI Gene ID

534332

UniProt

P98088

Swiss Prot

P98088

Host

Mouse

Species Reactivity

Cat,Chicken,Cow,Human,Monkey,Mouse,Rabbit,Rat

Reactivity

MUC5AC

Immunogen

M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le (a-b) patient

Target Antigen

MUC5AC

Clonality

Monoclonal

Clone

1-13M1

Type

Primary

Source

Animal

Origin

Animal

Applications

IHC, FFPE (published) |RIA (published) |WB (published)

Field of Research

Cancer, Mucins

Positive Control

Human colon or stomach (IHC).

Stability

2 years

Concentration

1 mg/mL

Buffer

PBS, no BSA, no azide

Molecular Weight

>1,000 kDa

References & Citations

Note: References for this clone sold by other suppliers may be listed for expected applications. Am J Respir Crit Care Med (2001) 163: 517-523. (IHC, FFPE) Oncotarget (2015) 6(6): 4274-4285. (WB) Int J Cancer (1998) 75:767-773. (RIA) Exp Eye Res (2007) 84(5): 939-950. (WB) Am J Gastroenterol (2017) 112(1): 172-183. (ELISA)