Paraxanthine-13C4,15N3

Paraxanthine-13C4,15N3 is the 13C-labeled and 15N-labeled Paraxanthine. Paraxanthine, a caffeine metabolite, provides protection against Dopaminergic cell death via stimulation of Ryanodine Receptor Channels.

Product Specifications

CAS Number

[1173018-79-5]

UNSPSC

12352005

Hazard Statement

H302

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/paraxanthine-13c4-15n3.html

Purity

99.80

Solubility

10 mM in DMSO|DMF : ≥ 20mg/mL|DMSO : ≥ 30mg/mL|Ethanol : ≥ 0.5mg/mL

Smiles

CN1C=[15N][13C]([15NH][13C]2=O)=[13C]1[13C]([15N]2C)=O

Molecular Formula

C3 13C4H8N 15N3O2

Molecular Weight

187.11

Precautions

H302

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Guerreiro S, et al. Paraxanthine, the primary metabolite of caffeine, provides protection against dopaminergic cell death via stimulation of ryanodine receptor channels. Mol Pharmacol. 2008 Oct;74 (4) :980-9.