Paraxanthine-13C4,15N3
Product Specifications
UNSPSC Description
Paraxanthine-13C4,15N3 is the 13C-labeled and 15N-labeled Paraxanthine. Paraxanthine, a caffeine metabolite, provides protection against Dopaminergic cell death via stimulation of Ryanodine Receptor Channels.
Target Antigen
Endogenous Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease;Others
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/paraxanthine-13c4-15n3.html
Purity
99.0
Solubility
10 mM in DMSO
Smiles
CN1C=[15N][13C]([15NH][13C]2=O)=[13C]1[13C]([15N]2C)=O
Molecular Weight
187.11
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Guerreiro S, et al. Paraxanthine, the primary metabolite of caffeine, provides protection against dopaminergic cell death via stimulation of ryanodine receptor channels. Mol Pharmacol. 2008 Oct;74(4):980-9.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W016498S1/Paraxanthine-13C4-15N3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W016498S1/Paraxanthine-13C4-15N3-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1173018-79-5
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