AChE/BChE-IN-18
AChE/BChE-IN-18 (Compound 4g) is a dual inhibitor of AChE/BChE , with a IC50 value of 0.315 μM for AchE. AChE/BChE-IN-18 is also a CB2R antagonist with a Ki value of 31 nM. AChE/BChE-IN-18 has neuroprotective activity[1].
Product Specifications
UNSPSC
12352005
Target
Cannabinoid Receptor; Cholinesterase (ChE)
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-bche-in-18.html
Solubility
10 mM in DMSO
Smiles
O=C(N(C)C)OC1=CC(CN2CC(SC(NC(C3(C4)C[C@H]5C[C@H](C[C@@H]4C5)C3)=O)=C6C(OC)=O)=C6CC2)=CC=C1
Molecular Formula
C30H37N3O5S
Molecular Weight
551.70
References & Citations
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161311/AChE-BChE-IN-18-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161311/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; CB2
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