PRAK Protein Active

<strong>PRAK Protein Active</strong>_x000D_ <strong>Catalog number:</strong> B2013826_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 15 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 55 kDa_x000D_ <strong>Supplied as:</strong> N/A_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −20°C_x000D_ <strong>Keywords:</strong> PRAK Protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Cargnello M, Roux PP. Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases Microbiol Mol Biol Rev. 2011 Mar;75(1):50-83._x000D_ 2: Moens U, Kostenko S. Structure and function of MK5/PRAK: the loner among the mitogen-activated protein kinase-activated protein kinases Biol Chem. 2013 Sep;394(9):1115-32._x000D_ 3: New L, Jiang Y, Zhao M, Liu K, Zhu W, Flood LJ, Kato Y, Parry GC, Han J. PRAK, a novel protein kinase regulated by the p38 MAP kinase EMBO J. 1998 Jun 15;17(12):3372-84._x000D_ 4: Wang Y, Wang W, Wu H, Zhou Y, Qin X, Wang Y, Wu J, Sun XY, Yang Y, Xu H, Qian X, Pang X, Li Y, Zhang Z, Han J, Zhang Y. The essential role of PRAK in tumor metastasis and its therapeutic potential Nat Commun. 2021 Mar 19;12(1):1736._x000D_ 5: Ronkina N, Johansen C, Bohlmann L, Lafera J, Menon MB, Tiedje C, Laa K, Turk BE, Iversen L, Kotlyarov A, Gaestel M. Comparative Analysis of Two Gene-Targeting Approaches Challenges the Tumor-Suppressive Role of the Protein Kinase MK5/PRAK PLoS One. 2015 Aug 21;10(8):e0136138._x000D_ 6: Mi L, Wang Y, Xu H, Wang Y, Wu J, Dai H, Zhang Y. PRAK Promotes the Pathogen Clearance by Macrophage Through Regulating Autophagy and Inflammasome Activation Front Immunol. 2021 Apr 16;12:618561._x000D_ 7: Tang J, Liu J, Li X, Zhong Y, Zhong T, Liu Y, Wang JH, Jiang Y. PRAK interacts with DJ-1 and prevents oxidative stress-induced cell death Oxid Med Cell Longev. 2014;2014:735618._x000D_ 8: Kostenko S, Jensen KL, Moens U. Phosphorylation of heat shock protein 40 (Hsp40/DnaJB1) by mitogen-activated protein kinase-activated protein kinase 5 (MK5/PRAK) Int J Biochem Cell Biol. 2014 Feb;47:29-37._x000D_ 9: Zhao Z, Wang Y, Gao Y, Ju Y, Zhao Y, Wu Z, Gao S, Zhang B, Pang X, Zhang Y, Wang W. The PRAK-NRF2 axis promotes the differentiation of Th17 cells by mediating the redox homeostasis and glycolysis Proc Natl Acad Sci U S A. 2023 May 9;120(19):e2212613120._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/31291142">10: Zhao YT, Du J, Yano N, Wang H, Wang J, Dubielecka PM, Zhang LX, Qin G, Zhuang S, Liu PY, Chin YE, Zhao TC. p38-Regulated/activated protein kinase plays a pivotal role in protecting heart against ischemia-reperfusion injury and preserving cardiac performance Am J Physiol Cell Physiol. 2019 Sep 1;317(3):C525-C533. </a>_x000D_ _x000D_ <strong>Products Related to PRAK Protein Active can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>