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DBIBB

DBIBB is a specific nonlipid agonist of the type 2 G protein coupled receptor for lysophosphatidic acid (LPA2) . DBIBB mitigates the gastrointestinal radiation syndrome, increases intestinal crypt survival and enterocyte proliferation, and reduces apoptosis. DBIBB represents a agent candidate capable of mitigating acute radiation syndrome caused by high-dose γ-radiation to the hematopoietic and gastrointestinal system[1].

Product Specifications

CAS Number

[1569309-92-7]

Product Name Alternative

5-(4-Phenoxybutoxy)psoralen,ZM-211975,ZK-76614

UNSPSC

12352005

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/dbibb.html

Concentration

10mM

Purity

98.07

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(N1CCCCNS(C2=C(C=CC=C2)C(O)=O)(=O)=O)C3=C4C(C=CC=C4C1=O)=CC=C3

Molecular Formula

C23H20N2O6S

Molecular Weight

452.48

References & Citations

[1]Patil R, et al. Combined mitigation of the gastrointestinal and hematopoietic acute radiation syndromes by an LPA2 receptor-specific nonlipid agonist. Chem Biol. 2015;22 (2) :206-216.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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