2-Acetylfuran-d3

2-Acetylfuran-d3 is deuterated labeled Citreoviridin (HY-N6745) . Citreoviridin, a toxin from Penicillium citreoviride NRRL 2579, inhibits brain synaptosomal Na+/K+-ATPase whereas in microsomes, both Na+/K+-ATPase and Mg2+-ATPase activities are significantly stimulated in a dose-dependent manner[1]. Citreoviridin inhibits cell proliferation and enhances apoptosis of human umbilical vein endothelial cells[2].

Product Specifications

Product Name Alternative

2-Furyl methyl ketone-d3

UNSPSC

12352005

Target

Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Field of Research

Others

Solubility

10 mM in DMSO

Smiles

CC(C1=C([2H])C([2H])=C([2H])O1)=O

Molecular Formula

C6H3D3O2

Molecular Weight

113.13

References & Citations

[1]Wang Y, et al. Amino acid-dependent formation pathways of 2-acetylfuran and 2,5-dimethyl-4-hydroxy-3[2H]-furanone in the Maillard reaction. Food Chemistry. 2009 Jul 1; 115 (1) :233-237.|[2]Banerjee R, et, al. Medicinal significance of furan derivatives: A Review . International Journal of Research in Phytochemistry and Pharmacology. 2015, 5 (3) :48-57.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.