Dimethyl sulfone

Dimethyl sulfone (Methyl Sulfonyl Methane) is a metabolic product of endogenous methanethiol metabolism and intestinal bacterial metabolism. Dimethyl sulfone inhibits choriocapillary endothelial (CCE) cell proliferation, also has many biological effects, including antiinflammatory, antioxidant, and local anesthetic effects that could be neuroprotective[1][2][3].

Product Specifications

CAS Number

[67-71-0]

UNSPSC

12352100

Hazard Statement

H302, H315, H319, H335

Target

Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Methane,_sulfonylbis-.html

Purity

99.60

Solubility

H2O : 50 mg/mL (ultrasonic)

Smiles

O=S(C)(C)=O

Molecular Formula

C2H6O2S

Molecular Weight

94.13

Precautions

H302, H315, H319, H335

References & Citations

[1]Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD) : National Library of Medicine (US) ; 2006-. Dimethyl Sulfone. 2022 Mar 21. |[2]Eter N, et al. DMSO mimics inhibitory effect of thalidomide on choriocapillary endothelial cell proliferation in culture. Br J Ophthalmol. 2002 Nov;86 (11) :1303-5. |[3]Shimizu S, et al. Dimethylsulfoxide (DMSO) treatment reduces infarction volume after permanent focal cerebral ischemia in rats. Neurosci Lett. 1997 Dec 19;239 (2-3) :125-7.