DX-9065a
Product Specifications
UNSPSC Description
DX-9065a is a selective, nonpeptidic, and orally active factor Xa (FXa) inhibitor with a Ki of 41 nM for human FXa. DX-9065a has low activity against other serine proteases. DX-9065a has strong anticoagulant actions[1][2].
Target Antigen
Factor Xa
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/dx-9065a.html
Smiles
N=C(N)C1=CC=C2C(C=C(C[C@H](C(O)=O)C3=CC=C(O[C@@H]4CN(C(C)=N)CC4)C=C3)C=C2)=C1.O.O.O.O.O.Cl
Molecular Weight
571.06
References & Citations
[1]Brigitte Kaiser. DX-9065a, a direct inhibitor of factor Xa. Cardiovasc Drug Rev. 2003 Summer;21(2):91-104. |[2]J M Herbert, et al. DX 9065A a novel, synthetic, selective and orally active inhibitor of factor Xa: in vitro and in vivo studies. J Pharmacol Exp Ther. 1996 Mar;276(3):1030-8.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-10722/DX-9065a-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-10722/
Clinical Information
Phase 2
CAS Number
155204-81-2
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