Calendic acid
Calendic acid (8 (E),10 (E),12 (Z) -Octadecatrienoic acid) is a conjugated polyunsaturated fatty acid (PUFA) that can be isolated from C. officinalis seed oil. Calendic acid has anticancer activity[1][2][3].
Product Specifications
CAS Number
5204-87-5
UNSPSC
12352211
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/calendic-acid.html
Smiles
CCCCC/C=C\C=C\C=C\CCCCCCC(O)=O
Molecular Formula
C18H30O2
Molecular Weight
278.43
References & Citations
[1]Crombie L, et al. The biosynthesis of calendic acid, octadeca- (8 E, 10 E, 12 Z) -trienoic, acid, by developing marigold seeds: origins of (E, E, Z) and (Z, E, Z) conjugated triene acids in higher plants. Journal of the Chemical Society, Perkin Transactions 1, 1985: 2425-2434. |[2]Yasui Y, et al. Growth inhibition and apoptosis induction by all-trans-conjugated linolenic acids on human colon cancer cells. Anticancer Res. 2006 May-Jun;26 (3A) :1855-60. |[3]Shinohara N, et al. jacaric acid, a linolenic acid isomer with a conjugated triene system, reduces stearoyl-CoA desaturase expression in liver of mice. J Oleo Sci. 2012;61 (8) :433-41.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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