Aminoacyl tRNA synthetase-IN-1
Selected Variant
HY-108939-01
Size: 1 mg
Aminoacyl tRNA synthetase-IN-1 is a bacterial aminoacyl tRNA synthetase (aaRS) inhibitor. Aminoacyl tRNA synthetase-IN-1 has inhibitory activity against S. aureus, E. faecalis and E.coli[1].
Product Specifications
CAS Number
219931-45-0
Product Name Alternative
IleSA
UNSPSC
12352005
Target
Aminoacyl-tRNA Synthetase; Bacterial
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Aminoacyl_tRNA_synthetase-IN-1.html
Purity
99.80
Solubility
DMSO : 65 mg/mL (ultrasonic)
Smiles
O[C@@H]1[C@@H](COS(=O)(NC([C@H]([C@@H](C)CC)N)=O)=O)O[C@@H](N2C(N=CN=C3N)=C3N=C2)[C@@H]1O
Molecular Formula
C16H25N7O7S
Molecular Weight
459.48
References & Citations
[1]Vondenhoff GH, et al. Microcin C and albomycin analogues with aryl-tetrazole substituents as nucleobase isosters areselective inhibitors of bacterial aminoacyl tRNA synthetases but lack efficient uptake. Chembiochem. 2012 Sep 3;13 (13) :1959-69.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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