Human Alpha-fetoprotein, His Tag (MALS verified)
Human Alpha-fetoprotein, His Tag (ALN-H52H9) is expressed from human 293 cells (HEK293) . It contains AA Arg 19 - Val 609 (Accession # P02771-1) .
Product Specifications
Background
Alpha-fetoprotein (AFP) is the first tumor marker with clinical application value found by human. AFP has an ability to induce the immune escapes through inhibiting the function of dendritic cells, natural killer cells, and T lymphocytes. By in vitro modification, the immunogenicity and immune response of AFP could be enhanced. AFP-modified immune cell vaccine or peptide vaccine has displayed the specific antitumor immunity against AFP-positive tumor cells and laid a better foundation for the immunotherapy of liver cancer. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 68.2 kDa. The protein migrates as 70-75 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
P02771-1
Expression Region
Arg 19 - Val 609
Host
HEK293
Target
Alpha-fetoprotein
Conjugation
Unconjugated
Tag
C-10xHis
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
95%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
68.2 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
500ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/ALN-H52H9.pdf
Species
Human
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
