JMJD7-IN-1
Product Specifications
UNSPSC Description
JMJD7-IN-1 is a potent JMJD7 inhibitor, with an IC50 of 6.62 μM. JMJD7-IN-1 shows good inhibitory activity against cells expressing a high level of JMJD7[1].
Target Antigen
Histone Demethylase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/jmjd7-in-1.html
Purity
98.57
Solubility
DMSO : 8.33 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(OC1=C2N=CC=CC2=C([N+]([O-])=O)C=C1)C3=CC=C(Cl)C=C3Cl
Molecular Weight
363.15
References & Citations
[1]Zhang W, et, al. Discovery of JMJD7 inhibitors with the aid of virtual screening and bioactivity evaluation. Bioorg Med Chem Lett. 2021 May 25;45:128139.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-132198/JMJD7-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-132198/JMJD7-IN-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
311316-96-8
Available Sizes
Curated Selection
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