NOD1 rabbit pAb
This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Oct 2009],
Product Specifications
Background
Product Name Alternative
Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4)
UniProt
Q9Y239
Swiss Prot
Q9Y239
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human NOD1 AA range: 290-340
Target
NOD1
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Molecular Weight
105kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
105kD
Fragment
IgG
Subcellular Location
Other Product Names
Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4)
Gene ID (Human)
10392
Available Sizes
Frequently Asked Questions
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