3-Decyl-5,5'-diphenyl-2-thioxo-4-imidazolidinone

3-Decyl-5,5'-diphenyl-2-thioxo-4-imidazolidinone (compound 45) is a potential inhibitor of fatty acid amide hydrolase (FAAH) (pI50: 5.89) and is active against CB (1) and CB (2) ) Lack of affinity for cannabinoid receptors[1].

Product Specifications

CAS Number

[875014-22-5]

UNSPSC

12352005

Hazard Statement

H225-H319-H336

Target

FAAH

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/3-decyl-5-5-diphenyl-2-thioxo-4-imidazolidinone.html

Solubility

10 mM in DMSO

Smiles

O=C1N(CCCCCCCCCC)C(NC1(C2=CC=CC=C2)C3=CC=CC=C3)=S

Molecular Formula

C25H32N2OS

Molecular Weight

408.60

Precautions

P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P370+P378-P403+P233-P403+P235-P405-P501

References & Citations

[1]Muccioli GG, et al. Substituted 2-thioxoimidazolidin-4-ones and imidazolidine-2,4-diones as fatty acid amide hydrolase inhibitors templates. J Med Chem. 2006 Jan 12;49 (1) :417-25.