Linalool,98% (stabilized with MEHQ)

Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities[1][2][3][4][5].

Product Specifications

CAS Number

[78-70-6]

UNSPSC

12352211

Hazard Statement

H227, H315, H317, H319, H402

Target

Apoptosis; Bacterial; Endogenous Metabolite; iGluR; TNF Receptor

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer; Infection; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/linalool.html

Purity

99.11

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C=CC(O)(C)CC/C=C(C)/C

Molecular Formula

C10H18O

Molecular Weight

154.25

Precautions

H227, H315, H317, H319, H402

References & Citations

[1]Oner Z1, et al. The protective and therapeutic effects of linalool against doxorubicin-induced cardiotoxicity in Wistar albino rats. Hum Exp Toxicol. 2019 Apr 12:960327119842634.|[2]Jun HJ, et al. Linalool is a PPARα ligand that reduces plasma TG levels and rewires the hepatic transcriptome and plasma metabolome. J Lipid Res. 2014 Jun;55 (6) :1098-110.|[3]Jana S, et al. Antitumorigenic potential of linalool is accompanied by modulation of oxidative stress: an in vivo study in sarcoma-180 solid tumor model. Nutr Cancer. 2014;66 (5) :835-48. |[4]Rodenak-Kladniew B, et al. Anti-cancer mechanisms of linalool and 1,8-cineole in non-small cell lung cancer A549 cells. Heliyon. 2020 Dec 15;6 (12) :e05639. |[5]An Q, et al. Recent updates on bioactive properties of linalool. Food Funct. 2021 Nov 1;12 (21) :10370-10389.